Peptides

Deep profiles for diligence—not product pages. Filter by goal or open any profile for mechanism, evidence, and citations.

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Showing 3 peptides tagged Sexual health.

Bremelanotide

Stronger clinical signal

A melanocortin-receptor agonist derived from Melanotan II research, FDA-approved as Vyleesi for hypoactive sexual desire disorder (HSDD) in premenopausal women. Notable as one of the only peptides in this category with a formal drug approval.

Sexual health

Melanotan II

Limited human data

A non-selective melanocortin-receptor agonist originally studied for skin tanning and erectile dysfunction, whose sexual-desire side effects led directly to the development of the FDA-approved drug bremelanotide (PT-141). Widely sold gray-market for tanning despite no approval for that use.

Sexual health

Kisspeptin-54

Limited human data

A naturally occurring neuropeptide that is the master regulator of the reproductive hormone axis, now in early clinical development as a fertility and psychosexual therapeutic. Distinct from the melanocortin-based sexual-health peptides—it works directly on the reproductive hormone cascade.

Sexual health

Evidence labels

EmergingMostly preclinical or early signals; human athletic data is thin.
Limited human dataSome human pharmacology or small studies; outcomes for fitness use remain limited.
Stronger clinical signalSupported by larger clinical trials in defined medical populations.

Same color code everywhere on STACKD: green = stronger clinical/human data, amber = limited human data or mechanism, slate = emerging/anecdotal, and oxblood = an in-house STACKD summary.